SAN-HUANG-YI-SHEN CAPSULE AMELIORATES DIABETIC KIDNEY DISEASE THROUGH INDUCING PINK1/PARKIN-MEDIATED MITOPHAGY AND INHIBITING THE ACTIVATION OF NLRP3 SIGNALING PATHWAY

San-Huang-Yi-Shen capsule (SHYS) has been used in the treatment of here diabetic kidney disease (DKD) in clinics.However, the mechanism of SHYS on DKD remains unclear.In this study, we used a high-fat diet combined with streptozocin (STZ) injection to establish a rat model of DKD, and different doses of SHYS were given by oral gavage to determine t

Pervasive developmental disorders are a group of neurodevelopmental disorders characterized by impairments in communication, reciprocal social interaction and restricted repetitive behaviors or interests.The term autism spectrum disorders (ASD) has been used to describe their variable presentation.Although the cause of these disorders is not yet kn

The present paper features various sources obtained from the Documentation Center of Contemporary History of Eastern Kazakhstan (the city of Semey).The research objective was to draw a detailed picture of the resettlement and economic conditions that special immigrants from the North Caucasus had to face in the Semipalatinsk region of the Kazakh Re

Daniel Erichsen1, Raffaelle yale law school colors Ferri2, David Gozal11Department of Pediatrics, University of Chicago, Chicago, IL, USA; 2Department of Neurology, Oasi Institute IRCCS, Troina, ItalyAbstract: Restless legs syndrome and periodic limb movement disorder of sleep are now recognized as prevalent, distinct, yet overlapping disorders aff

The use of metaphors in a computerized setting is not without its problems.Far from being a simple ‘tool’, in the ordinary sense, the computer has a built-in propensity for ‘capturing’ both its maker and its users.One could say that by its very structure, yale law school colors it defies the boundaries set for normal human activity: speed,